Important Safety Information
Important Safety Information

Mindbloom pairs individuals with licensed clinicians who are trained to diagnose and treat anxiety, depression, and other mental health conditions.  If one of the licensed clinicians, in their medical judgment, decides that ketamine is an appropriate treatment for an individual based on a clinical assessment, then the clinician may prescribe ketamine tablets that are compounded by pharmacies under Section 503A of the federal Food, Drug, and Cosmetic Act (FDCA).  Drugs compounded under Section 503A do not require FDA approval, and as such the FDA has not determined that the compounded ketamine prescribed is safe and effective for anxiety, depression, or other mental health conditions.  The use of ketamine for anxiety, depression, and many other mental health conditions, however, is supported by a body of scientific literature.  (Data on file).

Ketamine is a Schedule III controlled substance. Other drugs containing ketamine, which (unlike compounded drugs) are subject to FDA’s approval requirements, have been FDA-approved as an intravenous or intramuscular injection solution for induction and maintenance of general anesthesia. However, those drugs have not been FDA-approved for anxiety, depression, or other mental health conditions, and they have not been FDA-approved in tablet form. The approved label is available here.

Ketamine may cause serious side effects, including but not limited to risks of: sedation; dissociation; psychiatric events or worsening of psychiatric disorders, including problems in people with schizophrenia, severe personality disorders, or other serious mental disorders; dependence, abuse and misuse; anxiety; increases in blood pressure or heart rate; respiratory depression (breathing becomes slower and shallower and the lungs fail to exchange carbon dioxide and oxygen efficiently); lower urinary tract and bladder symptoms, including frequency of urination, urinary incontinence, pain urinating, passing blood in the urine, or reduced bladder size; altered sense of time; dry mouth; elevated intraocular or intracranial pressure; loss of appetite; confusion; nausea/vomiting; blurred vision; and slurred speech.

The FDA has advised that at-home administration of compounded ketamine may present additional risks because a health care provider is not available onsite to monitor for adverse outcomes resulting from sedation and dissociation.

Mindbloom’s protocols and guidance have been designed to minimize the likelihood of experiencing these side effects or other adverse effects, and should be followed carefully. Ketamine should only be taken as directed by the treating clinician.

Do not proceed with ketamine treatment if any of the following apply to you:

  • Allergic to ketamine
  • Symptoms of psychosis or mania
  • Uncontrolled high blood pressure
  • CHF or other serious heart problem
  • Severe breathing problem
  • History of elevated intraocular or intracranial pressure
  • History of hyperthyroidism
  • Other serious medical illness
  • Pregnant, nursing, or trying to become pregnant

Ketamine has been found to cause moderate psychological dependency in some users.

  • In rare cases, frequent, heavy users have reported increased frequency of urination, urinary incontinence, pain urinating, passing blood in the urine, or reduced bladder size
  • Ketamine may worsen problems in people with schizophrenia, severe personality disorders, or other serious mental disorders
  • Users with a personal or family history of psychosis should be cautious using any psychoactive substance, including ketamine, and discuss potential risks with your clinician before proceeding with treatment
  • The dissociative effects of ketamine may increase patient vulnerability and the risk of accidents

To promote positive outcomes and ensure safety, follow these ketamine treatment guidelines:

  • Do not operate a vehicle (e.g., car, motorcycle, bicycle) or heavy machinery following treatment until you’ve had a full night of sleep
  • Refrain from taking benzodiazepines or stimulants for 24 hours prior to treatment
  • Continue to take antihypertensive medication as prescribed
  • Do not take ketamine while hungover or with alcoholic beverages
  • Refrain from consuming solid foods within 3 hours prior to treatment and liquids within 1 hour prior to treatment
  • Ketamine treatment should never be conducted without a peer treatment monitor physically present

A peer-reviewed study of Mindbloom’s client treatment outcomes was published in the Journal of Affective Disorders in 2022, titled At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: Findings from a large, prospective, open-label effectiveness trial. The FDA has not evaluated head-to-head trials comparing the safety of ketamine to other medications that are FDA-approved for the treatment of depression, anxiety, or other psychiatric disorders. Although some clients report that they had more success with ketamine than with FDA-approved therapies, these outcomes may not be typical.

For more information about the informed consent that clients review and sign prior to treatment, please visit mindbloom.com/informed-consent.

At-home ketamine therapy that works

89%
saw results after 4 sessions1
95%
reported no side effects1
84%
who experienced significant improvements in an initial program maintained improvements or recovered in a second round of treatment2
100+ Clinical Studies. 20+ World-Class Institutions 

Is ketamine therapy right for you?

We get it. You’ve tried everything. Nothing works.

Ketamine therapy can provide breakthroughs for anxiety, depression, and PTSD when other treatments haven't worked.

Neuroplasticity creates lasting change.

Ketamine therapy creates neuroplasticity, your brain's ability to change. It helps your brain break out of loops of anxiety, depression, and negative self-talk so you can feel like yourself again.

Neuroplasticity creates lasting change.

Ketamine therapy creates neuroplasticity, your brain's ability to change. It helps your brain break out of loops of anxiety, depression, and negative self-talk so you can feel like yourself again.

Trusted by doctors for decades.

Ketamine has been on the World Health Organization's list of essential medicines for 40+ years.
Get started
708785
 sessions facilitated

Here’s what our clients have to say

Am I a candidate?
4.7 Average rating
"I am a veteran with PTSD and severe depression. Ketamine therapy has been life-changing for me."
Jacob
"I can honestly say almost immediately after my first session, I started noticing changes. I’ve become more empathetic, braver, and I’m kinder to myself."
Peter
"My PTSD and depression symptoms are gone. I absolutely love my life. For so long I didn’t, and this is an astounding new feeling."
Seth
"How I feel today is 1,000 times better than when I started. I’ve experienced things I didn’t know were possible."
Kayleigh
"I have an entirely new outlook on life. My past traumas no longer consume me 24/7, allowing my nervous system to rest & reset."
Marissa
"After my first session I said why didn’t I do this sooner? I will be a patient for life. The cost is so minimal to the results I see! I can cope with things I couldn’t before."
Michelle D.
"My guide put me at ease instantly and I felt so much better after my first session and it’s been really great so far. Years of therapy with no change and I noticed a significant change after my first [Mindbloom] session."
Paul R.
"I am a therapist myself and I have to say, I am impressed. The design of the program and the clinicians are excellent!"
Bo M.
"The best the thing I have ever tried to help with my depression! The way my mood has changed is unreal."
Howard J.
"My mind is quiet for maybe the first time ever! Mindbloom is changing my life for the better in more ways than I expected and I’m looking forward to the future. The clinical staff is so professional and my guide was great. I will recommend Mindbloom to my family and friends."
Teresa

Get Started in 3 Easy Steps

01
Take the 3-minute assessment
Take our quick survey to see if you're a candidate for treatment.
02
Meet with a licensed clinician
Meet with one of our expert clinicians, who will develop a personalized plan for you.
03
Start healing in 10-12 days
Our highly-trained guides will prepare you for your session and provide you with after-care support. Experience your first session in as little as 10 days.
Am I a candidate?

You’re not alone—we’ve built programs for you

 Starting at $159/Session

Overcome anxiety

Mindbloom for Anxiety with renowned psychologist Dr. Elizabeth Lombardo helps you explore the source of your anxiety, and provides you with the tools to let it go.

Relieve depression

Mindbloom for Depression targets the core of your depression, opening pathways to renewed hope and happiness.

Heal PTSD

Mindbloom for PTSD with trauma expert Shari Botwin, LCSW helps you heal your past in order to reclaim your future. Alleviate symptoms, regain control, and rediscover peace and joy in your daily life.

Get Unstuck

Led by Shaquile O’Neal’s “head coach for happiness”, Elizabeth Lombardo, PhD., you’ll learn to reignite your passion and unlock your inner strength.

FAQ

Who is eligible for Mindbloom treatment?

To be eligible for Mindbloom's transformative therapy programs, you must meet the following criteria:
• 18 years and older
• Residence in, or ability to visit one of the states in which Mindbloom is available
• A valid shipping address within one of these states to receive your prescription and Mindbloom materials
• A diagnosis of anxiety, depression, or PTSD by a Mindbloom clinician

Get started by taking our short quiz and schedule a virtual call with a Mindbloom clinician. They’ll help answer any questions you might have about Mindbloom and determine if you’re a good fit for treatment.

Who leads my treatment?

Your care team includes a psychiatric clinician, a guide, and Mindbloom's live support team.

Your clinician will build your personalized treatment plan, and actively monitor your progress to ensure you're getting medicine that's right for you.

Your guide will offer live 1:1 coaching and messaging to help you prepare for treatment and integrate your experiences to enable lasting transformation. Guides also host Group Integration Circles, where you can find connection and healing with fellow Mindbloom clients.

Our support team is standing by to help via SMS, email, and live chat.

How does ketamine work?

Ketamine can improve mental health in two ways: by improving your brain chemistry, and by providing a conscious therapeutic experience.

When people suffer from chronic anxiety, depression, and PTSD, the neurons in their brain become stunted with fewer connections. Ketamine helps repair this damage by stimulating neuroplasticity, or increased growth and flexibility. This can lead to reduction of negative thoughts and the formation of new neural connections—which is why we refer to Mindbloom treatment as healing at the root.  

The therapeutic ketamine experience can also provide positive psychological experiences, new perspectives, and an improvement in baseline mood and mindset. To learn more about the neuroscience of ketamine, click here.

How long does it take to see results?

Some clients see improvements right after their first session. For others, it can take a few more sessions to feel results, but 89% of clients see improvement after 4 sessions. In addition to immediate symptom relief, ketamine can help create new neural connections, facilitate emotional healing, and provide powerful insights for long-lasting, positive lifestyle changes.

Here are a few client quotes we love:
‍
“Before Mindbloom, feeling joy required so much work. After my very first session, I was planted in the present moment and immediately felt lighter. It stuck with me and just feels natural now.”
–Katie S.

“I had immediate relief from my anxiety and depression after my very first Mindbloom session. I’m so much more resilient to stress and am able to sit with and process my feelings now. I’m still feeling the benefits after my last session two months ago.”
—Adrienne E.

“After the first session, I started to feel a change in my mood and mindset. Each session thereafter feels like it continues to improve. The cloud of depression has dissipated and my anxiety has been extremely controllable - I feel like when I do get anxious, it comes for a moment and I am able to rationally process and let go.”
—Kaleb E.

What does ketamine feel like?

The felt experience of ketamine therapy is usually gentle, introspective, and positive. Our clients often report sensations of weightlessness and a dreamlike state. Each session typically lasts 45 minutes-1 hour, and you can resume your daily activities shortly thereafter. 

Your sessions take place at-home, and our clinical study demonstrated that a deeper level of comfort actually leads to improved results. Check out the research here.

See more

Start your healing journey today

Get started

Web tracking technologies in the following categories are used on our website. You may opt out of certain trackers as described below.

Necessary

These trackers are necessary for the website to function properly. They are usually set in response to actions made by you which amount to a request for services. You can set your browser to block or alert you about these trackers, but some parts of the site may no longer function.

Advertising

These trackers allow us to optimize advertising. They may be set on our site through advertising providers, which may use those trackers to build a profile of your interests and show you relevant ads on other sites and social media. You may opt out of these trackers.

Performance

These trackers allow us to monitor site visits and traffic sources so that we can measure, analyze, and improve the performance of our site. You may opt out of these trackers.

Confirm choices

We use cookies to enhance user experience, analyze web traffic, and assist in marketing. For further information, see our Privacy Policy.

Allow allReject allManage settings

Web tracking technologies in the following categories are used on our website. You may opt in to certain trackers as described below.

Allow all

Necessary

These trackers are necessary for the website to function properly. They are usually set in response to actions made by you which amount to a request for services. You can set your browser to block or alert you about these trackers, but some parts of the site may no longer function.

Advertising

These trackers allow us to optimize advertising. They may be set on our site through advertising providers, which may use those trackers to build a profile of your interests and show you relevant ads on other sites and social media. You may opt in to these trackers.

Performance

These trackers allow us to monitor site visits and traffic sources so that we can measure, analyze, and improve the performance of our site. You may opt in to these trackers.

Confirm choices
© 2025 Mindbloom, Inc. All rights reserved.
Privacy PolicySafety InformationTerms of UseInformed Consent