What is ketamine?
Ketamine is a transformational medicine of the mind. It can rapidly —often within an hour or two— lift the symptoms of anxiety, depression, and other conditions.
A Trusted and Widely-Used Medicine
Ketamine was approved by the FDA in 1970 as an anesthetic and analgesic, and has been listed on the World Health Organization's List of Essential Medicines since 1985.
Ketamine is also prescribed off-label to treat a wide range of mental health issues.
A Promising Treatment for Mental Health
Known for its anesthetic effects and therapeutic potential, ketamine is increasingly being used as a treatment for anxiety and depression.
At lower doses, ketamine can disrupt negative feelings and preoccupations and help the brain create new, healthier patterns.
How Does it Work?
Ketamine acts on the brain to provide relief from anxiety and depression.
Fuel Neural Growth
When people suffer from chronic anxiety and depression, their neurons become stunted with fewer connections.
Ketamine helps repair this damage by stimulating neuroplasticity and fertilizing the brain, restoring and strengthening new connections between neurons.
Reduce Negative Thoughts
Ketamine can also offer relief from negative thoughts by normalizing activity in a part of the brain known as the default mode network.
By altering connectivity in this part of the brain, ketamine can help people to break out of old thought patterns that cause anxiety and depression.
A Powerful Medicine
With its ability to promote the creation of new, healthy neural connections, ketamine can be a powerful tool for managing mental health.
For many people, the effects of ketamine therapy can last for months, with intermittent "boosters" extending the effects even further.
Gentle Onset Tablets
While intravenous and intramuscular administration methods can be abrupt, Mindbloom provides tablets that are dissolved under the tongue and gently take effect over 10-15 minutes.
Feelings of Relief
By temporarily silencing negative thoughts, ketamine therapy can offer much needed relief and healing.
Ketamine silenced the constant thoughts that have been torturing me for most of my life.”
Since using Mindbloom, I’ve experienced relief from my depression and anxiety.”
My experience culminated in the notion that everything is going to be okay.”
Gentle Experience
While everyone’s experience is different, many clients describe their Mindbloom sessions as gentle.
The most surprising part of my Mindbloom experience was how gentle and safe it felt.”
I expected a punch in the face, but it felt more like a tickle on the arm.”
I appreciate the comfort and safety of my own living room.”
New Perspective
Ketamine therapy facilitates new perspectives that can help us better process and move on from pain.
Mindbloom gave me a better perspective on anxiety, depression, and life itself.”
I’ve reframed my negative thoughts into positive ones.”
Mindbloom helped build a foundation that I needed to keep me from spiraling and feeling lost.”

Ketamine Research
Clinical research continues to demonstrate that ketamine can be used to treat mental health conditions and their symptoms successfully.
Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review
A study of ketamine's psychotherapeutic potential and systematic review of the extant evidence on ketamine's effects in treating mental health disorders.
Landmark Study of Ketamine Therapy
At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: Findings from a large, prospective, open-label effectiveness trial
Understanding How Ketamine Brings About Rapid Improvement in OCD
Obsessive-Compulsive Disorder (OCD) is a chronic and disabling disorder that costs the economy over $2 billion annually and represents a significant public health problem. This study aims to build on our discovery that a potent NMDA receptor antagonist, ketamine, has rapid (in hours) and robust therapeutic effects in OCD. The proposed projects test the acute mechanism of action of ketamine at the level of molecules, circuits, and network synchrony to determine how NMDA receptor antagonism modifies the underlying pathology of OCD to relieve repetitive thoughts and behaviors.