Mindbloom participated in the largest-ever clinical study on ketamine therapy. The study tracked 1,200+ Mindbloom clients over 4 sessions.

Clinical Study At a Glance
89%

of clients reported improvement in their depression and anxiety symptoms after 4 sessions

62%

of participants who reported suicidal ideation no longer reported any suicidal ideation after 4 sessions

95%

of clients reported no side effects from their ketamine treatment with Mindbloom

30%

of clients experiencing depression and anxiety achieved remission (or virtually no symptoms) after 4 sessions

Safety information
Important Safety Information

Mindbloom pairs individuals with licensed clinicians who are trained to diagnose and treat anxiety, depression, and other mental health conditions.  If one of the licensed clinicians, in their medical judgment, decides that ketamine is an appropriate treatment for an individual based on a clinical assessment, then the clinician may prescribe ketamine tablets that are compounded by pharmacies under Section 503A of the federal Food, Drug, and Cosmetic Act (FDCA).  Drugs compounded under Section 503A do not require FDA approval, and as such the FDA has not determined that the compounded ketamine prescribed is safe and effective for anxiety, depression, or other mental health conditions.  The use of ketamine for anxiety, depression, and many other mental health conditions, however, is supported by a body of scientific literature.  (Data on file).

Ketamine is a Schedule III controlled substance. Other drugs containing ketamine, which (unlike compounded drugs) are subject to FDA’s approval requirements, have been FDA-approved as an intravenous or intramuscular injection solution for induction and maintenance of general anesthesia. However, those drugs have not been FDA-approved for anxiety, depression, or other mental health conditions, and they have not been FDA-approved in tablet form. The approved label is available here.

Ketamine may cause serious side effects, including but not limited to risks of: sedation; dissociation; psychiatric events or worsening of psychiatric disorders, including problems in people with schizophrenia, severe personality disorders, or other serious mental disorders; dependence, abuse and misuse; anxiety; increases in blood pressure or heart rate; respiratory depression (breathing becomes slower and shallower and the lungs fail to exchange carbon dioxide and oxygen efficiently); lower urinary tract and bladder symptoms, including frequency of urination, urinary incontinence, pain urinating, passing blood in the urine, or reduced bladder size; altered sense of time; dry mouth; elevated intraocular or intracranial pressure; loss of appetite; confusion; nausea/vomiting; blurred vision; and slurred speech.

The FDA has advised that at-home administration of compounded ketamine may present additional risks because a health care provider is not available onsite to monitor for adverse outcomes resulting from sedation and dissociation.

Mindbloom’s protocols and guidance have been designed to minimize the likelihood of experiencing these side effects or other adverse effects, and should be followed carefully. Ketamine should only be taken as directed by the treating clinician.

Do not proceed with ketamine treatment if any of the following apply to you:

  • Allergic to ketamine
  • Symptoms of psychosis or mania
  • Uncontrolled high blood pressure
  • CHF or other serious heart problem
  • Severe breathing problem
  • History of elevated intraocular or intracranial pressure
  • History of hyperthyroidism
  • Other serious medical illness
  • Pregnant, nursing, or trying to become pregnant

Ketamine has been found to cause moderate psychological dependency in some users.

  • In rare cases, frequent, heavy users have reported increased frequency of urination, urinary incontinence, pain urinating, passing blood in the urine, or reduced bladder size
  • Ketamine may worsen problems in people with schizophrenia, severe personality disorders, or other serious mental disorders
  • Users with a personal or family history of psychosis should be cautious using any psychoactive substance, including ketamine, and discuss potential risks with your clinician before proceeding with treatment
  • The dissociative effects of ketamine may increase patient vulnerability and the risk of accidents

To promote positive outcomes and ensure safety, follow these ketamine treatment guidelines:

  • Do not operate a vehicle (e.g., car, motorcycle, bicycle) or heavy machinery following treatment until you’ve had a full night of sleep
  • Refrain from taking benzodiazepines or stimulants for 24 hours prior to treatment
  • Continue to take antihypertensive medication as prescribed
  • Do not take ketamine while hungover or with alcoholic beverages
  • Refrain from consuming solid foods within 3 hours prior to treatment and liquids within 1 hour prior to treatment
  • Ketamine treatment should never be conducted without a peer treatment monitor physically present

A peer-reviewed study of Mindbloom’s client treatment outcomes was published in the Journal of Affective Disorders in 2022, titled At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: Findings from a large, prospective, open-label effectiveness trial. The FDA has not evaluated head-to-head trials comparing the safety of ketamine to other medications that are FDA-approved for the treatment of depression, anxiety, or other psychiatric disorders. Although some clients report that they had more success with ketamine than with FDA-approved therapies, these outcomes may not be typical.

For more information about the informed consent that clients review and sign prior to treatment, please visit mindbloom.com/informed-consent.

Exceptional Outcomes

Compared to studies of traditional treatments, Mindbloom produced greater improvements in symptoms of anxiety and depression.

Psychotherapy1
41
%
SSRI Antidepressants2
47
%
IV Ketamine3
54
%
Mindbloom4
63
%
Percent of Patients with >50% Reduction of Depression Symptoms
References
1 | 2 | 3 | 4
Safety information
Important Safety Information

Mindbloom pairs individuals with licensed clinicians who are trained to diagnose and treat anxiety, depression, and other mental health conditions.  If one of the licensed clinicians, in their medical judgment, decides that ketamine is an appropriate treatment for an individual based on a clinical assessment, then the clinician may prescribe ketamine tablets that are compounded by pharmacies under Section 503A of the federal Food, Drug, and Cosmetic Act (FDCA).  Drugs compounded under Section 503A do not require FDA approval, and as such the FDA has not determined that the compounded ketamine prescribed is safe and effective for anxiety, depression, or other mental health conditions.  The use of ketamine for anxiety, depression, and many other mental health conditions, however, is supported by a body of scientific literature.  (Data on file).

Ketamine is a Schedule III controlled substance. Other drugs containing ketamine, which (unlike compounded drugs) are subject to FDA’s approval requirements, have been FDA-approved as an intravenous or intramuscular injection solution for induction and maintenance of general anesthesia. However, those drugs have not been FDA-approved for anxiety, depression, or other mental health conditions, and they have not been FDA-approved in tablet form. The approved label is available here.

Ketamine may cause serious side effects, including but not limited to risks of: sedation; dissociation; psychiatric events or worsening of psychiatric disorders, including problems in people with schizophrenia, severe personality disorders, or other serious mental disorders; dependence, abuse and misuse; anxiety; increases in blood pressure or heart rate; respiratory depression (breathing becomes slower and shallower and the lungs fail to exchange carbon dioxide and oxygen efficiently); lower urinary tract and bladder symptoms, including frequency of urination, urinary incontinence, pain urinating, passing blood in the urine, or reduced bladder size; altered sense of time; dry mouth; elevated intraocular or intracranial pressure; loss of appetite; confusion; nausea/vomiting; blurred vision; and slurred speech.

The FDA has advised that at-home administration of compounded ketamine may present additional risks because a health care provider is not available onsite to monitor for adverse outcomes resulting from sedation and dissociation.

Mindbloom’s protocols and guidance have been designed to minimize the likelihood of experiencing these side effects or other adverse effects, and should be followed carefully. Ketamine should only be taken as directed by the treating clinician.

Do not proceed with ketamine treatment if any of the following apply to you:

  • Allergic to ketamine
  • Symptoms of psychosis or mania
  • Uncontrolled high blood pressure
  • CHF or other serious heart problem
  • Severe breathing problem
  • History of elevated intraocular or intracranial pressure
  • History of hyperthyroidism
  • Other serious medical illness
  • Pregnant, nursing, or trying to become pregnant

Ketamine has been found to cause moderate psychological dependency in some users.

  • In rare cases, frequent, heavy users have reported increased frequency of urination, urinary incontinence, pain urinating, passing blood in the urine, or reduced bladder size
  • Ketamine may worsen problems in people with schizophrenia, severe personality disorders, or other serious mental disorders
  • Users with a personal or family history of psychosis should be cautious using any psychoactive substance, including ketamine, and discuss potential risks with your clinician before proceeding with treatment
  • The dissociative effects of ketamine may increase patient vulnerability and the risk of accidents

To promote positive outcomes and ensure safety, follow these ketamine treatment guidelines:

  • Do not operate a vehicle (e.g., car, motorcycle, bicycle) or heavy machinery following treatment until you’ve had a full night of sleep
  • Refrain from taking benzodiazepines or stimulants for 24 hours prior to treatment
  • Continue to take antihypertensive medication as prescribed
  • Do not take ketamine while hungover or with alcoholic beverages
  • Refrain from consuming solid foods within 3 hours prior to treatment and liquids within 1 hour prior to treatment
  • Ketamine treatment should never be conducted without a peer treatment monitor physically present

A peer-reviewed study of Mindbloom’s client treatment outcomes was published in the Journal of Affective Disorders in 2022, titled At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: Findings from a large, prospective, open-label effectiveness trial. The FDA has not evaluated head-to-head trials comparing the safety of ketamine to other medications that are FDA-approved for the treatment of depression, anxiety, or other psychiatric disorders. Although some clients report that they had more success with ketamine than with FDA-approved therapies, these outcomes may not be typical.

For more information about the informed consent that clients review and sign prior to treatment, please visit mindbloom.com/informed-consent.

Learn more about the landmark clinical study of at-home ketamine

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Client Stories

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Heather L.

My Mindbloom experience changed my life. I’ve learned so much about intentions, trust, and what I want my life to feel like. I feel energized, confident, and have built habits that help keep me in a positive mindspace.”

My Mindbloom experience changed my life. I’ve learned so much about intentions, trust, and what I want my life to feel like. I feel energized, confident, and have built habits that help keep me in a positive mindspace.”

Heather L.
Appreciation
Safety
Habits
Breakthroughs
Laura D.

With Mindbloom, it was like my mind took a deep breath of fresh air.”

With Mindbloom, it was like my mind took a deep breath of fresh air.”

Laura D.
Appreciation
Habits
Getting off Meds
Depression
Kodey G.

I started Mindbloom 6 months ago and today I’m completely off antidepressants. I feel like a human. I have an actual life. I wish this treatment was around years ago. I feel like I’m making up for lost time.”

I started Mindbloom 6 months ago and today I’m completely off antidepressants. I feel like a human. I have an actual life. I wish this treatment was around years ago. I feel like I’m making up for lost time.”

Kodey G.
Depression
Breakthroughs
Getting off Meds
Katie S.

I went back and forth for 3 years before starting ketamine therapy and wish I had made the decision way sooner. It 1000% made a difference.”

I went back and forth for 3 years before starting ketamine therapy and wish I had made the decision way sooner. It 1000% made a difference.”

Katie S.
Appreciation
Safety
Depression
Breakthroughs
Anxiety
Dan B.

Mindbloom helped me see my world in full color for the first time in my adult life.”

Mindbloom helped me see my world in full color for the first time in my adult life.”

Dan B.
Anxiety
Depression
Breakthroughs
Appreciation
Dana W.

I’ve been on and off meds since 2002 and if they work, it’s only for a brief time. I wish I would have done this treatment a year ago. It’s the only thing in over twenty years that has helped me. My only regret is not doing this sooner.”

I’ve been on and off meds since 2002 and if they work, it’s only for a brief time. I wish I would have done this treatment a year ago. It’s the only thing in over twenty years that has helped me. My only regret is not doing this sooner.”

Dana W.
Breakthroughs
Getting off Meds
Appreciation
Depression
Anxiety
Steve M.

Mindbloom is the complete package. I felt like the support and programming that was offered would take care of me on this sensitive journey.”

Mindbloom is the complete package. I felt like the support and programming that was offered would take care of me on this sensitive journey.”

Steve M.
Appreciation
Safety
Breakthroughs
Leslie L.

I suffered from crippling anxiety, depression, and became treatment-resistant. I tried Mindbloom out of literal desperation. Ketamine therapy has changed my life – perhaps even saved it.”

I suffered from crippling anxiety, depression, and became treatment-resistant. I tried Mindbloom out of literal desperation. Ketamine therapy has changed my life – perhaps even saved it.”

Leslie L.
Appreciation
Breakthroughs
Getting off Meds
Depression
Anxiety
Ryan B.

I had really intense social anxiety and felt imprisoned by my own mind. Mindbloom unlocked the door for me. For the first time in my adult life, I am fearless.”

I had really intense social anxiety and felt imprisoned by my own mind. Mindbloom unlocked the door for me. For the first time in my adult life, I am fearless.”

Ryan B.
Anxiety
Breakthroughs
Appreciation
James K.

For the first time, in a very long time, I woke up happy and excited for a new day.”

For the first time, in a very long time, I woke up happy and excited for a new day.”

James K.
Appreciation
Breakthroughs
Depression
Anxiety
Carrie C.

Mindbloom introduced me to a stronger version of myself. Someone who isn’t worried, afraid, anxious or depressed. I’m going to be OK.”

Mindbloom introduced me to a stronger version of myself. Someone who isn’t worried, afraid, anxious or depressed. I’m going to be OK.”

Carrie C.
Appreciation
Breakthroughs
Depression
Anxiety
Ariel H.

I have tried so many things for my depression and nothing worked. Mindbloom made a noticeable difference in my mood and uncovered the issues that were holding me back from growth.”

I have tried so many things for my depression and nothing worked. Mindbloom made a noticeable difference in my mood and uncovered the issues that were holding me back from growth.”

Ariel H.
Appreciation
Habits
Breakthroughs
Depression