Ketamine’s Interactivity with Common Psychiatric Medications

Medically reviewed by 
Chelsea Tersavich, PA-C
Published on 
December 19, 2022
Updated on 


  • Ketamine has a remarkable safety profile, and works with the majority of medications
  • Ketamine can interact with common psychiatric medications
  • Your clinician will let you know if any existing medications pose a risk
  • A table of common psychiatric medications and their interactivity profile is provided below

Before trying ketamine treatment, it’s important to know how any existing medications you take interact with this medicine. Your clinician will review your existing medications during your health screening to make sure ketamine therapy is the right fit for you.

If you have any questions or concerns whatsoever, bring these up to your clinician during these calls. 

The table below provides an overview of different classes of medication, examples of prescription medications, and their interactivity with ketamine treatment. 

You can find more information in this article if you wish to explore this further.


This article is for informational purposes only and is not intended to be a substitute for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. If you are in a life-threatening situation, call the National Suicide Prevention Line at +1 (800) 273-8255, call 911, or go to the nearest emergency room.

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