Beyond Microdosing: The Mindbloom Approach to Ketamine Therapy

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Published on 
July 14, 2023
Updated on 

While the practice of 'microdosing' – taking small, sub-perceptual doses of a substance – has garnered attention recently, at Mindbloom, we take a different approach. 

Mindbloom doesn’t provide microdosing services because we believe, and have demonstrated, that the dissociative/psychedelic experience facilitated by full ketamine doses leads to better long-term outcomes for our clients.

We believe that the benefits of ketamine treatment and psychedelic therapy extend beyond what microdosing is able to offer.

Addressing Root Causes

We structure everything in this way because our protocol aims not only to manage symptoms, but to help individuals address the root causes of these conditions. 

The experience induced by our dosing protocol can enable a deep exploration of oneself, providing the opportunity to identify and confront underlying or unresolved issues. 

Ketamine dosing sessions are typically followed by symptom alleviation, including temporary mood elevation, increased mental flexibility, and other neurobiological benefits – while also providing the opportunity for deeper work to unfold and key insights to arise throughout the course of treatment.

This depth of exploration is typically not possible with microdosing, which tends to focus more directly on symptom management.

Integration and Support

A cornerstone of Mindbloom's protocol is the emphasis on ongoing integration and support. 

We understand that the medicine experience is only one part of the healing journey. Clients are paired with both a psychiatric clinician and a guide throughout their program. 

This care team provides support before, during, and after sessions, helping clients process their experiences and integrate the insights gained into their daily lives. We also have a comprehensive library of therapeutic pathways, focusing on the skills and insights to help individuals cultivate self-love, overcome anxiety, heal depression, and more.

Microdosing can happen without this level of clinical or therapeutic support. This absence of detailed guidance and ongoing integration might limit the long-term benefits and durability of the treatment.

Personalization of Treatment

At Mindbloom, mental health treatment is as unique as the individual receiving it. 

That's why our protocol includes the possibility for personalization, with adjustments to dosage and treatment plans based on the individual's response and needs. 

Everything from the session music to the guide they work with can be personalized. Clients can choose the topics they want to focus on most and have a variety of support options between sessions. 

This dynamic approach contrasts with microdosing, where individuals are often following a one-size-fits-all regimen, without the benefit of professional oversight or deeper personalization.

The Full Experience Works

One key distinction between microdosing and Mindbloom's protocol lies in the psychedelic or dissociative experience that ketamine is proven to facilitate. 

The doses used in our protocol can induce a state of safe dissociation or psychedelic experience. It is these experiences and states of mind that can bring about key personal insights, important emotional distance, or a powerful moment for clients.

The results speak for themselves. Mindbloom was found to be more effective than traditional treatments like talk therapy, SSRI antidepressants, even other forms of ketamine therapy – with 63% of clients reporting a 50% or more reduction of their symptoms. 


In conclusion, while microdosing has its place in the wider discussion on novel mental health treatments, Mindbloom's ketamine therapy protocol offers unique advantages. 

It is designed to provide not only symptomatic relief but also transformative experiences that can aid in personal growth and healing. 

With a focus on individualized treatment, professional support, and the potential for profound insights, our protocol stands as a distinctive and promising approach in the mental health space and ketamine treatment generally.


This article is for informational purposes only and is not intended to be a substitute for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. If you are in a life-threatening situation, call the National Suicide Prevention Line at +1 (800) 273-8255, call 911, or go to the nearest emergency room.

Important FDA Safety Information

Ketamine is not FDA-approved for the treatment of depression or anxiety. Learn more about off-label uses here.

Side effects of ketamine treatment may include: altered sense of time, anxiety, blurred vision, diminished ability to see/hear/feel, dry mouth, elevated blood pressure or heart rate, elevated intraocular or intracranial pressure, excitability, loss of appetite, mental confusion, nausea/vomiting, nystagmus (rapid eye movements), restlessness, slurred speech, synesthesia (a mingling of the senses).

Do not proceed with ketamine treatment if any of the following apply to you:

  • Allergic to ketamine
  • Symptoms of psychosis or mania
  • Uncontrolled high blood pressure
  • CHF or other serious heart problem
  • Severe breathing problem
  • History of elevated intraocular or intracranial pressure
  • History of hyperthyroidism
  • Other serious medical illness
  • Pregnant, nursing, or trying to become pregnant

Ketamine has been reported to produce issues including, but not limited to, those listed below. However, lasting adverse side-effects are rare when medical protocols are carefully followed.

While ketamine has not been shown to be physically addictive, it has been shown to cause moderate psychological dependency in some recreational users.

  • In rare cases, frequent, heavy users have reported increased frequency of urination, urinary incontinence, pain urinating, passing blood in the urine, or reduced bladder size
  • Ketamine may worsen problems in people with schizophrenia, severe personality disorders, or other serious mental disorders.
  • Users with a personal or family history of psychosis should be cautious using any psychoactive substance, including ketamine, and discuss potential risks with your MindBloom® clinician before proceeding with treatment.
  • The dissociative effects of ketamine may increase patient vulnerability and the risk of accidents.

To promote positive outcomes and ensure safety, follow these ketamine treatment guidelines:

  • Do not operate a vehicle (e.g., car, motorcycle, bicycle) or heavy machinery following treatment until you’ve had a full night of sleep
  • Refrain from taking benzodiazepines or stimulants for 24 hours prior to treatment
  • Continue to take antihypertensive medication as prescribed
  • Avoid hangovers or alcohol intake
  • Refrain from consuming solid foods within 3 hours prior to treatment and liquids within 1 hour prior to treatment
  • Ketamine treatment should never be conducted without a monitor present to ensure your safety

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